Monograph: Serial electrodiagnostic testing: Utility and indications in adult neurological disorders-Article

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The monograph emphasizes the significance of serial electrodiagnostic testing in adult neurological disorders, highlighting its role in diagnosing, prognosticating, and monitoring changes over time. It discusses key indications including clarifying lesions, confirming progressive conditions, assessing nerve injury prognosis, and supplementing initial studies. The text illustrates how longitudinal assessments through repeat testing offer insights into disease progression and spatial abnormalities, emphasizing the need to interpret changes over time for accurate diagnoses and prognoses. Case examples demonstrate the utility of serial testing in conditions like carpal tunnel release outcomes and ALS. Furthermore, it explores challenges in distinguishing between conditions like Guillain-Barré Syndrome and nodopathies/paranodopathies, stressing the importance of integrating clinical history and lab results in electrodiagnosis interpretation. Moreover, it delves into the role of serial testing in CIDP diagnosis, treatment response prediction, traumatic nerve injury prognosis, and limitations such as minimal residual lesions. The document suggests avenues for future research to enhance the utility of serial electrodiagnosis. Ultimately, serial electrodiagnostic testing is essential for managing adult peripheral neurological disorders by monitoring electrophysiological changes to guide diagnosis, treatment, and prognosis decisions.

Keywords

serial electrodiagnostic testing

adult neurological disorders

diagnosis

prognosis

monitoring

lesions

nerve injury

disease progression

spatial abnormalities

CIDP diagnosis