Self-Assessment: Toxic Myopathies & Neuropathies | Advances in Duchenne Treatment & Management-Session recording

Video Transcription

Video Summary

The video discusses the case of an 83-year-old patient with progressive weakness, where a toxic myopathy from statin use is considered as the cause. The patient's symptoms, medical history, and laboratory findings are consistent with a statin-induced necrotizing myopathy. The rarity of symptomatic myopathy from statin use is mentioned, occurring in only 1-2 cases per 10,000 patient years. Other potential causes of muscle weakness, such as autoimmune disease and hypothyroidism, are considered but the temporal relationship to statin use supports the statin-induced myopathy as the most likely cause. The video also touches upon different types of toxic myopathies, including those induced by checkpoint inhibitors, colchicine, and antiretrovirals. The importance of evaluating clinical features, lab features, and electrodiagnostic findings to differentiate toxic myopathies from other causes of muscle weakness is emphasized. Recognizing and accurately diagnosing toxic myopathies is crucial for appropriate treatment and symptom management.<br /><br />No specific credits are mentioned in the summary.

Keywords

toxic myopathy

statin use

symptoms

medical history

laboratory findings

statin-induced necrotizing myopathy

rarity

autoimmune disease

hypothyroidism

temporal relationship

checkpoint inhibitors

colchicine

antiretrovirals