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Journal Review: Chronic inflammatory demyelinating polyradiculoneuropathy—Diagnostic pitfalls and treatment approach
Journal Review: Chronic inflammatory demyelinating polyradiculoneuropathy—Diagnostic pitfalls and treatment approach
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Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is characterized by progressive weakness and sensory loss, often affecting patientsʼ ability to walk and perform activities of daily living independently. With the lack of a diagnostic bio-marker, the diagnosis relies on clinical suspicion, clinical findings, and the demonstra-tion of demyelinating changes on electrodiagnostic (EDx) testing and nerve pathology. As a result, patients can often be misdiagnosed with CIDP and unneces-sarily treated with immunotherapy. Interpreting the EDx testing and cerebrospinal fluid findings in light of the clinical phenotype, recognizing atypical forms of CIDP, and screening for CIDP mimickers are the mainstays of the approach to patients suspected of having CIDP, and are detailed in this review. We also review the currently available treatment options, including intravenous immunoglobulin (IVIg), corticosteroids (CCS), and plasma exchange (PE), and discuss how to approach treatment-refractory cases. Finally, we emphasize the need to adopt objective outcome measures to monitor treatment response.




ACCREDITATION STATEMENT
The AANEM is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION
The AANEM designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. Credit expires 01/23/2024.

DISCLOSURE INFORMATION
No one involved in the planning of this CME activity had any relevant financial relationships to disclose. Any conflicts have been resolved by the Journal in accordance with the Muscle & Nerve editorial process.

FORMAT
PDF
Author
Amro M. Stino, MD; Elie Naddaf, MD; Peter J. Dyck, MD; P. James B. Dyck, MD.
Summary
Availability: On-Demand
Expires on Jan 23, 2024
Cost: Member: $0.00
Non-Member: $25.00
Credit Offered:
1 CME Credit
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