OasisLMS

Abstract
Muscle injury resulting in markedly elevated creatine kinase levels is termed rhabdomyolysis. The muscle damage can occur because of direct or indirect trauma, or it can be related to the use of certain medications, toxins, illicit drugs, or the presence of underlying inflammatory, metabolic, or genetic disorders with a predisposition for rhabdomyolysis. A detailed review of history can help in identifying the underlying etiology. Identification and removal of the triggering/inciting factor and noxious stimuli should be attempted as soon as possible. Careful evaluation for any complications and initiation of appropriate treatment are recommended. Aggressive fluid therapy, correction of metabolic derangement, and, when warranted, renal replacement therapy, form the mainstays of treatment.

Objectives: The objectives of this activity are to 1) Describe clinical features of Rhabdomyolysis, 2) Describe various etiologies and pathophysiology of rhabdomyolysis, 3) Discuss the diagnostic workup and management of rhabdomyolysis.

The AANEM is accredited by the American Council for Continuing Medical Education (ACCME) to providing continuing education for physicians. AANEM designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Kavita M. Grover has served as a paid consultant for Janssen, UCB, Amgen, and Kyverna. Naganand Sripathi has no conflicts of interest.
All relevant financial relationships have been mitigated according to ACCME standards.